MASI Longevity Science

Premium Fisetin

Clears senescent “zombie” cells

500 mg per serving

4.9 from 1,000+ reviews 1.37M+ servings
per daily serving
500 mg
made in Germany
Germany
independently tested
Swiss lab
See the Swiss lab reports

As we age, senescent or 'zombie' cells build up in the body. Fisetin is a plant flavonol studied for how it interacts with senescent cells and for pathways linked to cellular renewal and healthy aging.

Supports healthy aging

Senescent “zombie” cells

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Made in Germany
Third-party tested in Switzerland
Batch quality reports available

Product details

What is FISETIN?

Fisetin is a naturally occurring flavonol — a plant compound found in foods such as strawberries, apples, onions and cucumbers.

As we age, senescent or “zombie” cells build up in the body. These cells have stopped dividing but remain metabolically active. Scientists study cellular senescence as one of the biological processes involved in aging.

Fisetin is studied for how it interacts with senescent cells. Research has examined these effects in cells, human tissue samples and animals. Read the cellular-senescence study · PubMed.

Fisetin is also studied for antioxidant activity and cellular responses to oxidative stress — pathways relevant to healthy aging. Read the antioxidant study · PubMed review.

MASI Premium Fisetin supports a daily healthy-aging routine at the cellular level. Each capsule contains 250 mg of pure Fisetin. Each jar contains 60 vegan capsules. It is made in Germany with German raw materials and third-party tested in Switzerland for purity.

Ingredient research includes different doses, formulations and study designs. Human studies are still developing. Laboratory findings do not establish the same results for a daily supplement routine. This product is a dietary supplement, not a medicine.

Dosing

Each jar contains 60 vegan capsules. Each capsule contains 250 mg of pure Fisetin. Two capsules provide 500 mg.

How to take

  • 40–50 years: 1 capsule per day.
  • 50 years and above: 2 capsules per day.

At two capsules daily, one jar provides a 30-day supply. At one capsule daily, one jar lasts 60 days.

Purchase options

The 30-day subscription sends one jar every 4 weeks. The 90-day subscription sends three jars every 12 weeks. Supply names use the two-capsule daily serving; the billing intervals are shown separately in the purchase box.

One-time purchase includes one jar with no subscription. The ingredient label is available in the product image gallery. It lists rice bran.

Fisetin Benefits

Fisetin research focuses on cellular senescence, antioxidant activity and the cellular pathways involved in healthy aging.

Cellular renewal and healthy aging

Scientists have studied how fisetin interacts with senescent cells. A 2018 study examined cell cultures, human tissue samples and mice, helping establish the basis for further research. Read the study · PubMed.

Antioxidant activity

Laboratory studies examine how fisetin interacts with reactive molecules and oxidative stress, including cellular antioxidant pathways such as Nrf2. Read the laboratory study · Read the cell study.

Healthy aging at the cellular level

Fisetin research includes cellular pathways relevant to healthy aging. This is ingredient research, not a promise of clinical outcomes.

A consistent daily routine

One capsule provides 250 mg of Fisetin. Two capsules provide 500 mg. Directions: one capsule daily for ages 40–50, and two capsules daily for ages 50 and above. Each jar contains 60 vegan capsules.

Clinical studies & ingredient research

Explore published studies and registered human research on fisetin. Study labels distinguish human research, trial registrations and reviews. A trial registration describes a study; it is not a published result.

References

Explore the research on fisetin, cellular senescence, antioxidant activity and cellular signalling. Each reference links to the original publication.

  1. Fisetin and cellular senescenceYousefzadeh et al. · 2018 · eBioMedicine · cell, tissue and animal researchDOI: 10.1016/j.ebiom.2018.09.015
  2. Fisetin and cell-signalling pathwaysHuang et al. · 2018 · International Journal of Molecular Medicine · animal researchDOI: 10.3892/ijmm.2018.3582
  3. Fisetin and β-catenin signallingMolagoda et al. · 2021 · Scientific Reports · cell and zebrafish researchDOI: 10.1038/s41598-021-87257-0
  4. Fisetin, autophagy and cellular signallingSun et al. · 2021 · Food & Nutrition Research · cell researchDOI: 10.29219/fnr.v65.6355
  5. Fisetin as a dietary antioxidantKhan et al. · 2013 · Antioxidants & Redox Signaling · research reviewDOI: 10.1089/ars.2012.4901
  6. A review of fisetin antioxidant researchNaeimi and Alizadeh · 2017 · Trends in Food Science & Technology · research reviewDOI: 10.1016/j.tifs.2017.10.003
  7. Fisetin and oxidative DNA changesWang et al. · 2016 · Advanced Pharmaceutical Bulletin · laboratory researchDOI: 10.15171/apb.2016.037
  8. Fisetin, oxidative stress and Nrf2 signallingPark et al. · 2022 · Frontiers in Pharmacology · cell researchDOI: 10.3389/fphar.2022.927898
Swiss lab reports & quality
Swiss lab testingPremium Fisetin · Product-specific reports

Check the batch on your packaging against the report. Review the tests listed below for your batch.

Fisetin Microbiology test ↗
Fisetin Heavy metal test ↗

What real members say
about Premium Fisetin.

★★★★★

Premium Fisetin

I have much more energy and my appetite is under control.

Deborah

★★★★★

Just started on supplements, I add this with multi-vitamins and taurine

After hearing so much about Fisetin, I decided to give it a shot. It's been a game-changer for my energy levels and overall sense of wellness. Highly recommend it to my peers.

Lana

★★★★★

So, I gave those longevity pills a shot

So, I gave those longevity pills a shot, and honestly, I'm impressed. I didn't expect much at first, but over the past few weeks, I've noticed a marked improvement in my energy levels and overall mood.…

Beckett

★★★★★

Gave Fisetin a try and it's quietly revolutionizing my approach to aging and wellness

I've been using Fisetin for a couple of months now, and the difference in my cognitive function and physical stamina is noticeable. It's become a staple in my quest for healthy aging

Giselle

4 reviews shown: All reviews.

Fisetin · Studied for cellular renewal

What is Fisetin?

Fisetin is a plant flavonol found in foods such as strawberries and apples. Researchers study it for how it interacts with senescent (“zombie”) cells — cells that have stopped dividing but remain active as we age.

Published research has examined fisetin in cell, tissue and animal models for cellular renewal and healthy-aging pathways. Yousefzadeh et al., 2018 (PubMed) · Khan et al., 2013 (PubMed).

MASI Premium Fisetin is formulated to support healthy aging at the cellular level. It is a dietary supplement for a healthy-aging routine — not a medicine and not a substitute for professional care.

Each capsule contains 250 mg of pure Fisetin. 60 vegan capsules per jar. Made in Germany with German raw materials and third-party tested in Switzerland for purity.

Fisetin

Your daily routine

Supports cellular renewal and healthy aging.

Choose your plan

“I'm convinced that MASI supplements enhance cellular health and address several aging-related issues. It's a key component of my overall longevity strategy. This strategy includes MASI, regular exercise and a balanced diet, all working together to support a vibrant and healthy life in the years to come.”

Dr.Wolfgang Bucke, Ph.D.,Senior Pharmacist and Board Member

Pure transparency

From source to capsule.

See each step, from ingredients to delivery.

About our process

Follow the MASI Fisetin process from German raw materials to production, encapsulation and bottling in Germany. Independent Swiss laboratory reports provide additional information about the tested samples.

Open each step for the relevant details. The product gallery includes the ingredient label, and the laboratory section links to the original reports.

  1. Sourced in Germany

    MASI sources its raw materials in Germany. Its sourcing policy specifies 100% German materials and places the material origin at the start of the production process.

    German sourcing, manufacturing and bottling are separate steps. The product gallery shows the country-of-origin information, while independent laboratory reports provide information about the tested samples.

  2. Produced in Germany

    MASI produces its supplements in pharmaceutical-grade facilities in Germany. Production is followed by encapsulation and bottling in Germany.

    Ingredients and dietary suitability vary by formula. Premium Fisetin contains 250 mg of pure Fisetin per capsule. Review the Fisetin ingredient label in the gallery for the full formula information.

  3. Encapsulated in Germany

    The formula is placed into vegan capsules in Germany. Each capsule contains 250 mg of pure Fisetin, and two capsules provide a 500 mg serving.

    Each jar contains 60 capsules. The serving information above explains how the daily capsule count changes the number of days in a jar.

  4. Tested in Switzerland

    MASI uses independent Swiss laboratory testing. The Fisetin reports cover microbiology and heavy metals, including lead, mercury and cadmium.

    Open the original documents to see the sample details, laboratory methods and measured results. Each report identifies the tested sample and the parameters included in that analysis.

    View the Fisetin lab reports

  5. Bottled in Germany

    MASI bottles its supplements in a pharmaceutical-grade facility in Germany. Bottling follows production and encapsulation, keeping these stages within Germany.

    Each Fisetin jar contains 60 vegan capsules. The product label identifies the formula, ingredients and serving information. The gallery includes the label for review before purchase.

  6. Shipped from Europe

    Orders ship from Europe. Delivery options and shipping charges appear at checkout for the selected destination.

    A 90-day subscription sends three jars together every 12 weeks. A 30-day subscription sends one jar every 4 weeks. The purchase box shows the product charge and subscription interval.

Lab Results

Independent Fisetin lab reports.

Read the independent Swiss laboratory reports below. Each report applies to its stated product and batch.

  • Fast shipping

    Orders placed before 22:00 are shipped the same day

  • No import duties

    For order outside the EU we got you covered

  • Easy returns

    Money back within the first 14 days

Frequently Asked Questions

What is Fisetin?

Fisetin is a plant flavonol found in foods such as strawberries and apples. It is studied for how it interacts with senescent cells and for pathways linked to cellular renewal and healthy aging.

What are senescent cells?

As we age, senescent or “zombie” cells build up in the body — cells that have stopped dividing but remain active. Scientists study them as one process involved in aging.

How does Fisetin support healthy aging?

Research has examined fisetin’s interaction with senescent cells and antioxidant pathways. MASI Premium Fisetin is formulated to support healthy aging at the cellular level. It is a dietary supplement, not a medicine.

Does Fisetin have antioxidant properties?

Laboratory research studies fisetin’s antioxidant activity and cellular responses to oxidative stress — areas of interest for healthy-aging science.

How much Fisetin should I take daily?

How to take: 40–50 years, 1 capsule per day; 50 years and more, 2 capsules per day.

How much Fisetin is in each capsule?

Each capsule contains 250 mg of pure Fisetin.

How many capsules are in a jar?

60 vegan capsules per jar.

Where is MASI Premium Fisetin made?

Made in Germany with German raw materials.

Where is MASI Premium Fisetin tested?

Third-party tested in Switzerland for purity.

Are the capsules vegan?

60 vegan capsules per jar.

Premium Fisetin